Drug Discovery and Manufacturing News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Computer Model Predicts How Drugs Affect Heart Rhythm

UC Davis Health researchers have developed a computer model to screen drugs for unintended cardiac side effects, especially arrhythmia risk.

From The University of California, Davis 17 Apr 2020

Improving drug targets for asthma and rheumatoid arthritis

Researchers have found that immune T cells exhibit a range of responsiveness. This finding could offer insights into how the immune system of humans responds to infections and cancer, and what goes wrong in immune diseases.

16 Apr 2020

Researchers develop 3D cultured cells that mimic liver fibrosis

Headed by researchers from Japan-based Tokyo University of Agriculture and Technology (TUAT), a group of scientists has effectively established three-dimensional (3D) cultured tissue that imitates liver fibrosis, which is a major trait of non-alcoholic steatohepatitis (NASH).

2 Apr 2020