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Rice chemist receives NIH grant to speed up drug design

Rice University chemist László Kürti and his lab have received a prestigious Maximizing Investigators' Research grant from the National Institutes of Health to speed up drug design by simplifying the synthesis of essential precursors.

9 Apr 2020

Personalized biohybrid microrobots for therapeutic cargo delivery

Tiny biohybrid robots on the micrometer scale can swim through the body and deliver drugs to tumors or provide other cargo-carrying functions.

8 Apr 2020

Study reveals shape-shifting enzyme dihydrofolate reductase is associated with catalysis

Researchers from the University of Groningen have visualized the characteristics of a single enzyme within a nanopore.

8 Apr 2020

Scientists discover unexpected pathway by which brown fat can burn energy

When we are exposed to sufficient cold or exercise, small clusters of brown fat cells in our bodies begin to burn up energy.

7 Apr 2020

Researchers gain insight into synthesis and functions of lipids found in tears

New understandings of how lipids function within tears could lead to better drugs for treating dry eye disease.

7 Apr 2020

Study sheds light on the mechanism of cell division

There is no clear consensus on when exactly cells decide to divide. For four decades, the answer provided in the textbook was that this decision takes place in the initial phase of the existence of a cell—that is, soon after a mother cell divides into daughter cells.

7 Apr 2020

Scientists discover molecular mechanism that regulates the body's immune sentinels

A team at the Centro Nacional de Investigaciones Cardiovasculares, working in partnership with researchers at Mount Sinai Hospital in New York, has discovered a new molecular mechanism mediated by nuclear receptors that determines the identity and expansion of macrophages--one of the cell types that act as immune sentinels in the body.

6 Apr 2020

Protein Abundant In The Heart Plays Key Role In Blood Clotting

Heart protein cardiac myosin, which is released into the body when a person suffers a heart attack, can cause blood to thicken or clot.

3 Apr 2020

Researchers develop 3D cultured cells that mimic liver fibrosis

Headed by researchers from Japan-based Tokyo University of Agriculture and Technology (TUAT), a group of scientists has effectively established three-dimensional (3D) cultured tissue that imitates liver fibrosis, which is a major trait of non-alcoholic steatohepatitis (NASH).

2 Apr 2020

Virtual Cell Predicts How Close Tumor Environment Influences Cancer Metastasis

The process of metastasis, which allows carcinoma cells to leave the tumor of origin, is still the leading cause of mortality for cancer patients.

2 Apr 2020

Discovery Of New Biomarker In Blood Could Lead To Early Test For Alzheimer's Disease

Researchers discovered that high blood levels of RNA produced by the PHGDH gene could serve as a biomarker for early detection of Alzheimer's disease.

From UC San Diego 2 Apr 2020

Study reveals coconut oil reduces metabolic syndrome associated with obesity

An animal study has found that obese females who consumed a small amount of coconut oil every day, in spite of having a high-fat diet, exhibited reduced metabolic syndrome—several risk factors that increase the possibilities of developing heart disease, diabetes, and stroke.

1 Apr 2020

New cell therapy proves effective in human and mouse tumor models

A new study published recently in eLife reports that researchers have developed new immunotherapy that eliminates solid tumors in mice without causing detrimental side effects.

1 Apr 2020

Patients with chronic myopathy can benefit from cell-aging drug and exercise

According to a researcher from Hokkaido University and collaborators from Japan-based Sapporo Medical University, exercise can boost strength in muscle-degenerating disorders only when aging occurs in a certain type of muscle cell.

1 Apr 2020

Fatty acids could be effective platform for drug delivery

Triglycerides have long been treated as a threat to human health. Now, researchers believe they could be an effective drug delivery platform.

1 Apr 2020

New strategy can help treat diabetes and other diseases

Transplanted islet cells that release insulin during very low blood sugar levels offer a potential way for treating diabetes.

From Massachusetts Institute of Technology (MIT) 31 Mar 2020

Gene deletion from insulin-producing cells prevents type 1 diabetes in mice

According to a new study performed by the University of Wisconsin-Madison, deleting a gene from insulin-producing cells prevents the development of Type 1 diabetes in mice, by sparing the cells from being attacked by their own immune system.

27 Mar 2020

Researchers engineer skin cells into brain cells for effective regenerative therapies

Precise activation of selfish genetic elements called LINE-1 (L1) retrotransposons is essential to develop functional brain cells in a lab dish.

27 Mar 2020

Study finds large gaps in the scientific knowledge of cannabis genome

In an international study published recently, researchers from the University of Saskatchewan report that combined scientific effort would be needed to assemble and map the genome of cannabis to unravel its full potential for human health and agriculture.

26 Mar 2020

How do stem cells promote neuronal growth in tissue regeneration?

Stem cells are capable of producing a wide range of particular tissues and are used more and more in clinical applications—for example, these cells are used for replacing a cartilage or bone.

24 Mar 2020