Cell Biology

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Stem cell strategy can help improve the effectiveness of cardiac repair

Human stem cells have been typically perceived as one of the potential cell sources for cardiac regeneration treatment. However, the substandard performance following transplantation into the failing hearts has limited their applications in clinical use.

30 Mar 2020

Gene deletion from insulin-producing cells prevents type 1 diabetes in mice

According to a new study performed by the University of Wisconsin-Madison, deleting a gene from insulin-producing cells prevents the development of Type 1 diabetes in mice, by sparing the cells from being attacked by their own immune system.

27 Mar 2020

New model helps determine techniques used by cells to increase their sensitivity

The human body’s capability to identify foreign material, disease, and the location of food sources and toxins is governed by a mixture of chemicals surrounding the cells and also their ability to “read” these chemicals. Cells are extremely sensitive.

27 Mar 2020

Researchers engineer skin cells into brain cells for effective regenerative therapies

Precise activation of selfish genetic elements called LINE-1 (L1) retrotransposons is essential to develop functional brain cells in a lab dish.

27 Mar 2020

Study shows cellular protein shredders can help combat cancer

An international study, headed by the University of Bonn and Ulm University, has analyzed how the “protein shredder” of a cell can be particularly programmed to combat cancer.

26 Mar 2020

Simulations reveal effects of spatial organization within cells on genetic processes

Scientists at the University of Illinois at Urbana-Champaign have created the first-ever computational model of a human cell and simulated its behavior for 15 minutes.

26 Mar 2020

How do stem cells promote neuronal growth in tissue regeneration?

Stem cells are capable of producing a wide range of particular tissues and are used more and more in clinical applications—for example, these cells are used for replacing a cartilage or bone.

24 Mar 2020

Zscan4 protein protects against deadly DNA damage during early embryonic development

In association with Stanford University, a working group from the Division of Cell and Developmental Biology at the Medical University of Vienna (MedUni Vienna) has discovered the role of a crucial factor that plays a role in early embryonic development.

23 Mar 2020

Study offers detailed molecular map of interaction patterns of GPCR and different G protein subtypes

G protein-coupled receptors (GPCRs) have crucial roles to play in cell signal transduction and can be used as vital therapeutic targets for several diseases.

20 Mar 2020

Multi-tissue model shows how different tissues account for various inflammatory diseases

Biological engineers from Massachusetts Institute of Technology (MIT) have developed a multi-tissue model that allows them to analyze the associations between the immune system and different organs, on a dedicated microfluidic platform embedded with human cells.

From Massachusetts Institute of Technology (MIT) 19 Mar 2020

Role of MCL1 in maintaining intestinal homeostasis

An international group of scientists from the University of Zurich, the University Hospital Zurich, Heidelberg, and Glasgow have discovered a new function of MCL1, the protein that regulates cell death.

19 Mar 2020

Parallel neural pathways bypassing brain’s frequency control enable animals to move faster

The speed at which a person runs determines the end result, whether running to win an Olympic gold or to escape a predator.

13 Mar 2020

Biochemical, analytical high-throughput methods used to map proteome of plants

Plants play a crucial role in the survival of life on earth. They offer oxygen for breathing and food for all organisms, as well as regulate the planet’s climate. Proteins are vital in controlling all aspects of life, including plants.

13 Mar 2020

Researchers uncover a surprising property of blood stem cells

A Franco-German research team led by Prof. Michael Sieweke, from the Center for Regenerative Therapies TU Dresden and the Center of Immunology of Marseille Luminy, today uncovered a surprising property of blood stem cells: not only do they ensure the continuous renewal of blood cells and contribute to the immune response triggered by an infection, but they can also remember previous infectious encounters to drive a more rapid and more efficient immune response in the future.

13 Mar 2020

Changes in cell death patterns in the nervous system could allow a species to adapt to its environment

According to research conducted in fruit flies at the Francis Crick Institute, the University of Lausanne (UNIL) and the Max Planck Institute for Chemical Ecology, zombie cells tend to develop into functional neurons when the death of neurons is stopped during brain growth.

12 Mar 2020

Copper-binding protein influences migration of breast cancer cells

At the Chalmers University of Technology, scientists have demonstrated that the Atox1 protein, which is highly concentrated in breast cancer cells, takes part in a process—the process through which cancer cells spread.

11 Mar 2020

New technology used to probe and catalog activity of cells involved in muscle repair

The repair of muscles is a crowded, complex task. When different types of cells work together to regenerate new tissue, they bump around, rattling and trying to coordinate with one another.

11 Mar 2020

Study explores the impact of solute carriers on the activity and potency of cytotoxic drugs

At the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, scientists have investigated how solute carriers (SLCs)—a large class of membrane transport proteins—affect the activity and potency of cytotoxic drugs, for example, those used to treat leukemia and other cancers.

10 Mar 2020

New chromosome-level detectors developed to monitor cellular activity

For researchers investigating the regulatory processes in cells that are vital to all life, an innovative system that amplifies gene expression signals could be a turning point.

10 Mar 2020

A new breakthrough could lead to better approaches for preventing breast cancer metastasis

New breakthrough in breast cancer could enable the development of better approaches to prevent the spread of cancer cells to other organs in the body, thereby effectively bringing down mortality in patients suffering from breast cancer.

9 Mar 2020

Cell Biology

Stem cell strategy can help improve the effectiveness of cardiac repair

Gene deletion from insulin-producing cells prevents type 1 diabetes in mice

New model helps determine techniques used by cells to increase their sensitivity

Researchers engineer skin cells into brain cells for effective regenerative therapies

Study shows cellular protein shredders can help combat cancer

Simulations reveal effects of spatial organization within cells on genetic processes

How do stem cells promote neuronal growth in tissue regeneration?

Zscan4 protein protects against deadly DNA damage during early embryonic development

Study offers detailed molecular map of interaction patterns of GPCR and different G protein subtypes

Multi-tissue model shows how different tissues account for various inflammatory diseases

Role of MCL1 in maintaining intestinal homeostasis

Parallel neural pathways bypassing brain’s frequency control enable animals to move faster

Biochemical, analytical high-throughput methods used to map proteome of plants

Researchers uncover a surprising property of blood stem cells

Changes in cell death patterns in the nervous system could allow a species to adapt to its environment

Copper-binding protein influences migration of breast cancer cells

New technology used to probe and catalog activity of cells involved in muscle repair

Study explores the impact of solute carriers on the activity and potency of cytotoxic drugs

New chromosome-level detectors developed to monitor cellular activity

A new breakthrough could lead to better approaches for preventing breast cancer metastasis

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