Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

NEUROG3 Gene Plays Key Role in Pancreas Development

Different cells in the human pancreas play important roles in blood sugar regulation. Neurogenin 3 (NEUROG3) is a gene found in pancreatic cells.

1 Sep 2023

The Pathogenic Mechanism Underpinning MEPAN Syndrome

New research published in Nature Metabolism discovered the pathogenic mechanism driving mitochondrial enoyl reductase protein-associated neurodegeneration (MEPAN) syndrome, a rare pediatric neurodegenerative disease.

1 Sep 2023

New Gene Therapy Shows Promise in Treating Gliomas

The University of Michigan Department of Neurosurgery and Rogel Cancer Center study demonstrates enticing early results that a therapy merging cell-killing and immune-stimulating drugs is effective and safe in prolonging survival for patients with gliomas, an extremely aggressive form of brain cancer.

1 Sep 2023

Case Western Reserve Biochemists Find New Approach to Stop Cancer Growth

Case Western Reserve University biochemical researchers have identified a new function of a key protein that leads to cancer–a finding they believe could lead to more effective treatments for a range of cancers and other diseases.

1 Sep 2023

The Last Piece of Our Genome: Sequencing the Y Chromosome

A full sequence of the Y chromosome, a feat that has challenged scientists for years, has been accomplished for the first time. In this interview, we speak to Dylan Taylor about this impactful research and how it may shape our understanding of human genetics.

1 Sep 2023

Algae Reveals Plant Development Across 600 Million Years

Large-scale gene expression data were generated by an international team of researchers, led by a team from the University of Göttingen, to examine the molecular networks that function in Mesotaenium endlicherianum, a common single-celled alga that is among the closest living relatives of land plants. Nature Plants reported their findings.

31 Aug 2023

MAGE Technology Helps Reveal the Potency of Antibiotics

By substituting each of the 20 amino acid alternatives found in nature for one of the 38 amino acid components that make up the rifampicin binding site on E. coli, the study authors were able to produce 760 distinct RNAP mutants. The development of this mutant pool was then examined under various circumstances, including rifampicin therapy.

31 Aug 2023

Crick Researchers Identify Stem Cells in Thymus for First Time

For the first time, Francis Crick Institute researchers have discovered stem cells in the human thymus. These cells provide a possible new target for research into immunological disorders, cancer, and immune system stimulation.

31 Aug 2023

Novel Genotyping Method Reveals New Insights into Lettuce Genomics

A consortium of European investigators used SPET for the first time in lettuce (Lactuca sativa L.) as part of the European Evaluation Network (EVA) of the European Cooperative Programme for Plant Genetic Resources (ECPGR), with the goal of studying its genetic diversity and identifying genomic regions that underpin agronomically important traits.

31 Aug 2023

Gene Expression Analysis of Algae Sheds Light on Plant Terrestrialization

The Earth's surface is covered by plants. They make up the majority of biomass on land and exhibit a wide range of diversity, from mosses to trees.

31 Aug 2023

New Strain of Marine Bacteria with Distinct Characteristics

Researchers discovered a new type of marine bacteria with distinct traits on the ocean floor.

30 Aug 2023

Genetic Risk of Depression Linked to Increased Risk of Other Psychiatric Disorders

Recent research reveals that people who are hospitalized for depression are at an increased risk of developing conditions like substance abuse, bipolar disorder, schizophrenia, and anxiety, depending on their genetic predisposition to the individual disorder.

30 Aug 2023

Scale Biosciences Continues Commercial Expansion with Introduction of New and Differentiated Single Cell Methylation and Single Cell RNA Sequencing Solutions

Scale Biosciences, Inc. (ScaleBioTM), an innovator in single cell sequencing leveraging combinatorial indexing technologies, today announced an expansion of their product portfolio to enable a broader range of single cell omics experiments and unlock new translational research applications.

30 Aug 2023

The Art of Neuroscience: Synaptic Transmission and Plasticity in Isolated Neurons

Studying the complex interactions between synaptic nerve endings as well as their development has now become much easier.

30 Aug 2023

T Cells Infiltrate Brain and Worsen Alzheimer's Pathology, Study Finds

Cognitive decline associated with Alzheimer's disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive inflammation in the brain triggered by amyloid beta deposits and tau tangles, two hallmarks of the disease.

28 Aug 2023

NSL Complex Regulates Intraciliary Transport Genes in Multiple Cell Types

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown in both fruit flies and mammals to regulate the expression of thousands of genes. Abrogation of the NSL genes causes the organism to die, which gives rise to the complex’s unusual name.

28 Aug 2023

Gene Therapy Shows Promise for Muscular Dystrophy Patients

Researchers at Cincinnati Children’s Hospital reveal how damage to the cell’s energy factory causes muscle wasting. Closing a pore in the mitochondrial membrane in gene-edited mice prevents disease progression.

28 Aug 2023

Understanding the Importance of Entrepreneurship in the Life Sciences Community

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Maciej Grajewski, the Co-Founder and Chief Technology Officer at SG Papertronics, about all things bio-entrepreneurship.

From Society for Laboratory Automation and Screening (SLAS) 28 Aug 2023

Study Identifies 39 Genetic Mutations Associated With Heart Failure

In a new study co-led by investigators at the United States Department of Veterans Affairs and Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, a global team of scientists conducted one of the largest genetic association studies on heart failure to date.

25 Aug 2023

Researchers Shed Light on Complex Interplay Between Taste Perception and Immune Function

A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study published in iScience, by Hong Wang, PhD, an Associate Member at the Monell Chemical Sense Center, and colleagues sheds light on the mechanisms involved in the complex interplay between taste perception and immune function.

25 Aug 2023