Electron Microscopy News and Research

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Scientists reveal how 9-1-1 clamp attaches to DNA damage site for initiating effective repair

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.

22 Mar 2022

Researchers use GP2 and UMOD to prevent urinary tract infection

A team led by Karolinska Institute used AI and structural biology to learn more about two similar proteins that protect against bacterial infection in the urinary tract.

16 Mar 2022

Cryo-EM reveals how a bacterial protein senses and rescues stalled ribosomes

As a molecular machine found in the cells of all organisms, the ribosome is responsible for making new proteins.

11 Mar 2022

Scientists observe first high-resolution 3D image of muscle protein nebulin

Skeletal and heart muscle owe their function as stable biological machines to the outstanding accuracy with which their sarcomeres are assembled.

22 Feb 2022

Study develops AI-based method to help analyze protein complexes

A new technique for analyzing proteins has been developed by researchers at Martin Luther University Halle-Wittenberg (MLU) and the European Molecular Biology Laboratory in Hamburg.

21 Feb 2022

3D structure of protein channel helps shed light on sensitive touch response of Venus fly traps

Scientists at Scripps Research have revealed the three-dimensional structure of Flycatcher1, an aptly named protein channel that may enable Venus fly trap plants to snap shut in response to prey.

18 Feb 2022

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022

Novel function of anti-HIV-1 antibodies discovered using robust microscopy techniques

Using cutting-edge imaging methods on in vitro virus cells, researchers from the Institut Pasteur, CNRS, VRI, and Université de Paris found a role of anti-HIV-1 antibodies.

From Institut Pasteur 14 Feb 2022

First 3D structure of regulator protein elucidated in almost atomic resolution

Proteins are indispensable components in living organisms. They are not only "building material" for the body – they also make molecular communication between cells possible, they are needed for nerve impulses to occur, and they control chemical reactions.

3 Feb 2022

Scientists visualize protein machinery of respiration with unparalleled precision

Oxygen and sugar are the basis of life for animals, plants, fungi and many bacteria. The metabolic process called respiration makes it possible to convert food into energy for the cells.

1 Feb 2022

Experts unravel a new form of communication between brain cells

Scientists discovered hundreds of proteins that are constantly transferred throughout the healthy brain in small membrane-enclosed sacs.

31 Jan 2022

Structural proteomics approaches show promise for treating neurodegenerative diseases

Two researchers from Skoltech and McGill University have published a review of the promising research field known as structural proteomics in the influential journal Chemical Reviews.

28 Jan 2022

Researchers use cryo-EM to rapidly characterize antibodies at atomic level

Scripps Research scientists have found a mechanism that may be able to bypass one of the critical steps in current vaccine production.

24 Jan 2022

Scientists shed light on mechanisms responsible for maturation of the splicing machinery

Alternative Splicing is an extraordinarily complex process that requires the coordinated action of multiple proteins, each specialized in very specific functions. These proteins are assembled and matured, forming a kind of consortium of proteins that perform these gene reading functions.

31 Dec 2021

Researchers grow intestinal organoids to study why bats infected with viruses do not succumb to diseases

Experiments attempting to explain why bats can be infected with many viruses at a time without succumbing to diseases such as COVID-19-;knowledge that could help us to reduce the threat to humans of infectious disease-;have struggled until now with the fact that live wild bats make poor research subjects.

30 Dec 2021

Study identifies novel function for existing protein

Researchers recently identified a new role of the protein tBID, which was to date linked to the regulatory role in cancer and cell death. But tBID also directly mediates apoptosis (controlled cell death).

23 Dec 2021

Study provides novel insights into biological energy conversion

The respiratory chain performs a major role in the cell’s energy metabolism. It is localized in mitochondria—the power plants of the cell.

21 Dec 2021

First molecular structure of TDP-43 could pave the way for new ALS therapies

Scientists have determined for the first time the structure of the molecule associated with amyotrophic lateral sclerosis (ALS) and multiple other neurodegenerative diseases.

9 Dec 2021

Covalent Metrology and JEOL Announce Partnership, Silicon Valley Demonstration Facility

December 07, 2021 – Sunnyvale, CA. Covalent Metrology, a leading North American provider of analytical services, announces its partnership with JEOL a global leader in the development of cutting-edge scientific instruments used in microscopy, analytical chemistry, and materials characterization.

From JEOL USA, Inc. 7 Dec 2021

Scientists unravel the structure of octopus-like Lassa viral polymerase

Endemic in Western African countries, Lassa virus is transmitted to humans through food or household items that are contaminated with the urine or faeces of Mastomys rats.

7 Dec 2021