Fluorescence Microscopy News and Research

RSS

Fluorescence microscopy is an imaging technique used to examine cells and their internal components. Specific cellular components can be labeled with fluorophores.

Study illustrates the concept of cool microscopy

Fluorescence light microscopy has the unique ability to observe cellular processes over a scale that bridges four orders of magnitude. Yet, its application to living cells is fundamentally limited by the very rapid and unceasing movement of molecules that define its living state.

From The Max Planck Institute 14 Dec 2021

New two-photon microscope provides unprecedented brain-imaging ability

Advancing our understanding of the human brain will require new insights into how neural circuitry works in mammals, including laboratory mice.

3 Dec 2021

Bacterial-fungal interactions are far more common and diverse than previously known

In a novel, broad assessment of bacterial-fungal interactions, researchers using unique bioinformatics found that fungi host a remarkable diversity of bacteria, making bacterial-fungal interactions far more common and diverse than previously known.

20 Oct 2021

Novel process enables 3D imaging of human organs with micrometer resolution

Scientists recently demonstrated a process by which specific cell types in human organs can be investigated with micrometer precision.

15 Sep 2021

Scientists develop new tool to identify neuronal proteins in animal models

Scientists, for the first time, developed a successful method for pinpointing proteins within different kinds of neurons in the brain of a living animal.

16 Aug 2021

Researchers employ 3D holographic microscopy to visualize bioplastic in living cells

Scientists from KAIST inspected the accumulation of bioplastic granules in living bacterial cells with the help of 3D holographic microscopy.

29 Jul 2021

New method for generating metabolic profiles of individual cells

Researchers from the EMBL and the German Cancer Research Center (DKFZ) demonstrated a new technique to create metabolic profiles of individual cells.

8 Jul 2021

Fluorescence microscopy and deep learning predict viral infections

Researchers have now used fluorescence images from live cells to train an artificial neural network to reliably detect cells that are infected by herpes viruses.

22 Jun 2021

Scientists discover the central role of LRRC8A gene in cellular ability to survive osmotic shock

Cells have to constantly adapt to their surroundings in order to survive. A sudden increase in the environmental levels of an osmolyte, such as salt, causes cells to lose water and shrink. In a matter of seconds, they activate a mechanism that allows them to recover their initial water volume and avoid dying.

2 Jun 2021

New microscope helps observe the whole body of the embryo

A research group led by Takashi Saito, of the Ehime University Graduate School of Medicine, developed a 2-photon excitation light-sheet fluorescence microscope which (1) lowers phototoxicity, (2) extends the field of view, and (3) heightens spatial resolution.

31 May 2021

Study could help develop peptide siRNA carrier for human oral cancer

MUSC Hollings Cancer Center researchers are exploring the use of peptide carriers for the delivery of small RNA drugs as a novel treatment for cancer. The team's recent work, published online March 19 in the Molecular Therapy - Nucleic Acids journal, lays the foundation for developing a clinically relevant peptide carrier RNAi-based drug treatment strategy for human oral cancer.

25 May 2021

Study reveals RNA regulatory mechanisms within transcription-translation couplings

To gain a better understanding of how bacterial RNA gives rise to proteins scientists are now focusing on the special way this process takes place in bacteria.

15 Apr 2021

Simple buffers can prevent photoblueing effect in microscopy

Advances in fluorescence microscopy make it viable to image molecular complexes or individual molecules in cells with a spatial resolution of up to 20 nm.

1 Mar 2021

New statistical study shows how pairs of cancer cells interact

One of the fundamental principles of biology is the fact that cells are motile and make contact with one another.

17 Feb 2021

New insights into the biology of chytrid fungus responsible for deadly skin infection

Researchers at the University of Massachusetts Amherst have gained new insight into the biological processes of a chytrid fungus responsible for a deadly skin infection devastating frog populations worldwide.

9 Feb 2021

Breast cancer-on-a-chip for rapid screening of immunotherapeutic drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called "checkpoint proteins."

3 Feb 2021

Novel microscopy system for scanless 3D measurement with submicron resolution

The National Institute of Information and Communications Technology (NICT), Tohoku University, Toin University of Yokohama, and Japan Science and Technology Agency (JST) have succeeded in developing a scanless high-speed holographic fluorescence microscopy system with submicron resolution for a 3D space.

1 Feb 2021

Study shows TALEN is five times more efficient than CRISPR-Cas9 tool

Using single-molecule imaging, scientists have compared the CRISPR-Cas9 and TALEN genome editing tools.

28 Jan 2021

New approach to biomaterial production may ease environmental burden of forestry, agriculture

It takes a lot to make a wooden table. Grow a tree, cut it down, transport it, mill it ... you get the point. It's a decades-long process. Luis Fernando Velásquez-García suggests a simpler solution: "If you want a table, then you should just grow a table."

22 Jan 2021

Altered sugar composition impacts cell-to-surface adhesion

Biotechnologists measure the forces with which algae cells adhere to surfaces and move on them. How can cells adhere to surfaces and move on them? This is a question that was investigated by an international team of researchers headed by Prof. Michael Hippler from the University of Münster and Prof. Kaiyao Huang from the Institute of Hydrobiology (Chinese Academy of Sciences, Wuhan, China).

4 Jan 2021