Drug Discovery and Manufacturing News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

New screening method allows identification of drugs that glue proteins together

Scientists developed a new screening method that tests the effectiveness of therapeutic molecules developed to “glue” proteins together in the body.

9 Jul 2021

Emerging variants of COVID-19 could be treated with a new anticoagulant drug

The capacity of the COVID-19 virus’s spikes to bind to human cells may be hampered by molecules from the same family as the anticoagulant medication heparin.

9 Jul 2021

New technique boosts the efficacy of future malaria vaccines

A new technique for obtaining pure malaria parasites from infected mosquitos could speed up the development of novel, more powerful malaria vaccinations.

21 Jun 2021

New process reinvigorates the search for natural drugs to treat cancers

A research team has devised a new method that might revitalize the hunt for natural product medications to treat viral infections, cancer, and other diseases.

4 Jun 2021

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Antibiotics used to treat common bacterial infections may potentially be used to treat human illnesses such as cancer, at least theoretically.

27 May 2021

Single fingerprint can help determine whether someone has touched or ingested class A drugs

A research team explains how they were able to distinguish between the fingerprints of those who handled cocaine with those who have taken the medicine.

From University of Surrey 20 May 2021

Study: Turning off molecular switch could help treat melanoma

Melanoma accounts for only about 1% of skin cancers but leads to most of the skin cancer-related deaths.

20 May 2021

New, patented method helps drugs to easily enter the cells

A new technique known as Progressive Mechanoporation allows genes or drugs to enter cells by mechanically disrupting cell membranes for a brief period.

13 May 2021

Study shows metabolic pathways by which Mycobacterium tuberculosis consumes its favorite nutrients

Mycobacterium tuberculosis is remarkable because it can live in the human host for decades.

From University of Surrey 13 May 2021

Genetically encoded sensor helps detect hallucinogenic substances

Researchers at the University of California, Davis, have created a genetically encoded sensor for detecting hallucinogenic substances.

From The University of California, Davis 29 Apr 2021

Developing a portable tool to detect street drug ‘spice’

AZoLifeSciences speaks to researchers from the University of Bath about their latest research that led to the development of a device that can detect 'spice'.

From University of Bath 28 Apr 2021

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

New method can improve the drug testing process

When developing a new drug, the first question is, “does it work?” and the second question is, “is it harmful?”

9 Apr 2021

Researchers take a key step toward new drugs and vaccines for combating COVID-19

Scientists have achieved a huge step toward new vaccines and drugs for fighting against COVID-19.

6 Apr 2021

New AI-based method can lead to faster, low-cost development of protein-based drugs

Thanks to a newly published study by scientists, artificial intelligence (AI) can now create novel and functionally active proteins.

1 Apr 2021

Study provides clues for designing more effective antiviral drugs

An international research team from the University of Turku based in Finland and PennState University based in the United States has solved an ancient puzzle of how living organisms differentiate between DNA and RNA building blocks at the time of gene expression, offering new possibilities for designing novel antiviral medications.

18 Mar 2021