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Scientists shed light on mechanisms responsible for maturation of the splicing machinery

Alternative Splicing is an extraordinarily complex process that requires the coordinated action of multiple proteins, each specialized in very specific functions. These proteins are assembled and matured, forming a kind of consortium of proteins that perform these gene reading functions.

31 Dec 2021

Researchers grow intestinal organoids to study why bats infected with viruses do not succumb to diseases

Experiments attempting to explain why bats can be infected with many viruses at a time without succumbing to diseases such as COVID-19-;knowledge that could help us to reduce the threat to humans of infectious disease-;have struggled until now with the fact that live wild bats make poor research subjects.

30 Dec 2021

"Heavy" hydrogen makes drugs to have a longer effect

Hydrogen (abbreviated "H") is the lightest of all elements. It usually consists only of a positively charged proton and a negatively charged electron and is also called protium in this form. But there are also two heavier hydrogen isotopes, deuterium and tritium.

24 Dec 2021

Study identifies novel function for existing protein

Researchers recently identified a new role of the protein tBID, which was to date linked to the regulatory role in cancer and cell death. But tBID also directly mediates apoptosis (controlled cell death).

23 Dec 2021

Study provides novel insights into biological energy conversion

The respiratory chain performs a major role in the cell’s energy metabolism. It is localized in mitochondria—the power plants of the cell.

21 Dec 2021

New methods help chemists to understand how bacteria turn light into chemical energy

Chemists have come to a deeper understanding of how photosynthetic bacteria convert light into chemical energy and discovered why one step in the process may be more robust than previously realized, according to a new study published this week in Proceedings of the National Academy of Sciences.

17 Dec 2021

First molecular structure of TDP-43 could pave the way for new ALS therapies

Scientists have determined for the first time the structure of the molecule associated with amyotrophic lateral sclerosis (ALS) and multiple other neurodegenerative diseases.

9 Dec 2021

Highly optimized X-ray process delivers high-resolution 3D images of cells

Viral pathogens such as the SARS-CoV-2 coronavirus alter the interior structure of the cells they infect.

8 Dec 2021

Covalent Metrology and JEOL Announce Partnership, Silicon Valley Demonstration Facility

December 07, 2021 – Sunnyvale, CA. Covalent Metrology, a leading North American provider of analytical services, announces its partnership with JEOL a global leader in the development of cutting-edge scientific instruments used in microscopy, analytical chemistry, and materials characterization.

From JEOL USA, Inc. 7 Dec 2021

Scientists unravel the structure of octopus-like Lassa viral polymerase

Endemic in Western African countries, Lassa virus is transmitted to humans through food or household items that are contaminated with the urine or faeces of Mastomys rats.

7 Dec 2021

Research reveals link between biological evolution and climate change

An international team including Rutgers-New Brunswick scientists utilized artificial intelligence techniques and traced the evolution of coccolithophores—an ocean-dwelling phytoplankton group, above 2.8 million years.

From Rutgers University 7 Dec 2021

Experts analyze key protein complexes involved in DNA replication and repair

Cryogenic electron microscopy (cryo-EM) allows scientists to investigate the assembly of DNA replication machinery where DNA is damaged.

25 Nov 2021

Viral RNA undergoes conformational changes to hijack host cells, says study

Scientists from the University of Colorado Anschutz Medical Campus recently identified how an RNA molecule from a virus develops a complex, three-dimensional structure, and is capable of changing its shape to hijack host proteins.

25 Nov 2021

Study discovers new species of green microalga in São Paulo

A group led by researchers affiliated with the Phycology Laboratory at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, have discovered a new species of green microalga in a reservoir located in the northwest of the state.

24 Nov 2021

Cancer cells disarm immune cells by hijacking mitochondria, says research

Researchers utilized the power of nanotechnology to identify a novel means that cancer cells use to disarm their would-be cellular attackers.

19 Nov 2021

Robust electron microscope provides mechanistic insight into protein degradation

Proteins are the building blocks of all living things and numerous studies are carried out to determine how these proteins are made and their function.

19 Nov 2021

Experts determine the molecular structure of a gut protein

Researchers from EMBL Hamburg and the Centre for Structural Systems Biology (CSSB) identified the molecular structure of a gut protein that aids the absorption of various drugs. This finding can help produce drugs that reach target tissues more effectively.

8 Nov 2021