Drug Discovery and Manufacturing News and Research

RSS

The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Further Reading

Microneedles For Therapeutic Gene Delivery

Microneedles For Therapeutic Gene Delivery

There is great potential in gene therapy for treating certain types of cancer and genetic defects, immunological diseases, wounds and infections.

7 Oct 2020

New method can help test vaccine formulations

New method can help test vaccine formulations

Scientists are casting a net for nanoparticles. They have now identified a new technique for producing nanoparticles from a simple, self-assembling polymer.

6 Oct 2020

80-year-old antibiotic redesigned for new medical uses

80-year-old antibiotic redesigned for new medical uses

Physicians and scientists have long searched the natural world for chemicals that can improve human health.

5 Oct 2020

Millimetre-Precision Drug Delivery To The Brain

Millimetre-Precision Drug Delivery To The Brain

Researchers have developed a method for concentrating and releasing drugs in the brain with pinpoint accuracy.

5 Oct 2020

Scientists identify new ingredient that makes vaccine more effective

Scientists identify new ingredient that makes vaccine more effective

A number of vaccines contain ingredients known as adjuvants that make them more effective by triggering a more powerful immune response.

5 Oct 2020

Researchers identify a promising treatment for COVID-19 infection

Researchers identify a promising treatment for COVID-19 infection

An effective method for treating the 2003 SARS epidemic, also works on the closely associated SARS-CoV-2 virus.

5 Oct 2020

Study shows patients can benefit from personalized cancer therapy

Study shows patients can benefit from personalized cancer therapy

Scientists have shown that patients, who are receiving care for cancer, have a greater chance of surviving if they received personalized cancer treatment.

From UC San Diego 5 Oct 2020

Gut bacteria may play a role in the treatment of prostate cancer

Gut bacteria may play a role in the treatment of prostate cancer

New research shows how the gut microbiome communicates with an oral drug in prostate cancer patients.

30 Sep 2020

Druggable pocket in SARS-CoV-2 Spike protein can help eliminate COVID-19

Druggable pocket in SARS-CoV-2 Spike protein can help eliminate COVID-19

Researchers have identified a druggable pocket in the SARS-CoV-2 Spike protein that could be utilized to prevent the virus from infecting human cells.

24 Sep 2020

Researchers identify new way to treat chronic myelogenous leukemia

Researchers identify new way to treat chronic myelogenous leukemia

Scientists have detected a second path to treat chronic myelogenous leukemia, which is known to affect older adults, despite its resistance to drugs.

22 Sep 2020

How do hallucinogenic drugs exert their actions on the brain?

How do hallucinogenic drugs exert their actions on the brain?

Not much is known about the fundamental mechanisms in the brain of hallucinogenic drugs and the way they induce their hallucinogenic effects.

21 Sep 2020

New study can help reduce the failure rate of drug development for various diseases

New study can help reduce the failure rate of drug development for various diseases

A novel genetic analysis of blood protein concentrations has shown how genetic information can be applied to support the prioritization of drug targets.

9 Sep 2020

Researchers develop antibacterial agent to treat drug-resistant infections

Researchers develop antibacterial agent to treat drug-resistant infections

Methicillin-resistant Staphylococcus aureus (MRSA) is the most lethal drug-resistant bacteria and is also one of the most common bacterial pathogens.

3 Sep 2020

Study shows Annexin molecule promotes resistance to anticancer drugs

Study shows Annexin molecule promotes resistance to anticancer drugs

Headed by Kumamoto University (Japan), a collaborative study has identified a novel mechanism for anticancer drug resistance in gastric cancer.

24 Aug 2020

Newly developed transplantable human cells can help cure type 1 diabetes

Newly developed transplantable human cells can help cure type 1 diabetes

Researchers have made a significant advancement in the quest for a safe, effective treatment for type 1 diabetes.

20 Aug 2020

Study shows how herpesvirus invades human cells and causes chickenpox

Study shows how herpesvirus invades human cells and causes chickenpox

Inspite of several years of research, scientists are still clueless about how herpesviruses penetrate the human cells.

20 Aug 2020

New technique could accelerate drug research for various diseases

New technique could accelerate drug research for various diseases

Alicyclic compounds are groups of organic chemical compounds that have led to the development of a number of medications.

19 Aug 2020

Researchers develop new drugs to eradicate parasitic worms

Researchers develop new drugs to eradicate parasitic worms

In this breakthrough method, parasitic worms are prevented from using alternative metabolism routes offered by microbes living inside them.

12 Aug 2020

Discovery Shows Promise For Treating Huntington's Disease

Discovery Shows Promise For Treating Huntington's Disease

Huntington disease is a progressive debilitating brain disorder that causes uncontrolled movements, psychological problems, and loss of cognition.

6 Aug 2020

A New Way of Killing Tuberculosis

A New Way of Killing Tuberculosis

AZoLifeSciences speaks to Dr. Tim Blower about his research into tuberculosis, and how the discovery of a new toxin could lead to new anti-TB drugs.

From Durham University 5 Aug 2020

Hi, I'm Azthena, you can trust me to find commercial scientific answers from AZoNetwork.com.

To start a conversation, please log into your AZoProfile account first, or create a new account.

Registered members can chat with Azthena, request quotations, download pdf's, brochures and subscribe to our related newsletter content.

A few things you need to know before we start. Please read and accept to continue.

Use of “Azthena” is subject to the terms and conditions of use as set out by OpenAI.
Content provided on any AZoNetwork sites are subject to the site Terms & Conditions and Privacy Policy.
Large Language Models can make mistakes. Consider checking important information.

I understand, and agree to receive occasional emails about Azthena such as usage tips and new feature announcements.

Please check the box above to proceed.

Great. Ask your question.

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.