Microscopy

Microscopy is an umbrella term to describe techniques used to analyse small samples that cannot be viewed with the naked eye. There is a wide range of microscopy techniques and scientific instruments available that can be used depending on their applications. A microscope magnifies tiny objects or samples and can provide a wealth of vital information about their cell structure, contamination, parasites and so much more.

This hub will contain all of the information you need to know about microscopy and will include the latest news and fascinating research articles. Whether you are looking to expand your knowledge of compound microscopes or fluorescence microscopy, you will find it all here under featured articles and the latest interviews.

What is Microscopy?

The word microscope is derived from the Greek “mikros”, meaning small and, “skopein” meaning to see.

Microscopy and Artificial Intelligence

Scanning Electron Microscopy (SEM): An Overview

Investigating the Intersection between Microscopy and Healthcare

Fluorescence Microscopy: An Overview

Using Scanning Electron Microscopy to Image SARS-CoV-2

Confocal Microscopy: An Overview

Electron Microscopy: An Overview

Using Electron Microscopy to Detect Viruses

Applications of Scanning Electron Microscopy

Uses of Microscopy in Forensics

What are Polarized Light Microscopes and How Do They Work?

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Role of Microscopy in Ballistics

Applications of Polarized Light Microscopy

Phase-Contrast Microscopy: An Overview

Avoiding Cell Death in Fluorescence Microscopy

Photobleaching in Fluorescence Microscopy

TEM Imaging Modes

Visualizing the 3D Architecture of Tissues

What is Confocal Imaging?

The Determination of Post-Mortem Interval (PMI) Using Transmission Electron Microscopy

The Digital Evolution of Microscopy

What is FIB-SEM?

‘Staining’ of Biological Samples when Using Electron Microscopy: Why stain density matters

Why Size Matters in Microscopy

Light Microscopy Techniques in Virology: An Overview

Identifying Corpses Using Microscopy

What is Environmental Forensic Microscopy?

Imaging Techniques in Drug Discovery

Microscopy and Artificial Intelligence

Deep Learning in Fluorescence Microscopy

Optimizing Live Cell Imaging with FRET Microscopy

‘Staining’ of Biological Samples when Using Electron Microscopy: Why stain density matters

Applications of IVIS (In Vivo Imaging Systems)

Advances in Scanning Electron Microscopy

Microscopes in Forensic Epidemiology- An Overview

What is 3D X-Ray Microscopy?

TEM Imaging Modes

Imaging Nuclear Structures Using AFM

Advances in Fluorescence Microscopy

Cryo-Electron Microscopy: An Overview

Confocal Reflection Microscopy for Cell Migration Studies

Transmission Electron Microscopy: An Overview

How do Epifluorescence Microscopes Work?

What is High-Resolution TEM (HR-TEM)?

Applications of 3D X-ray Microscopy

Two-photon Microscopy Principles and Methodology

Advantages and Limitations of Fluorescence Microscopy

Optical Microscopy: An Overview

Light Microscopy Techniques in Virology: An Overview

Optimizing Live Cell Imaging with FRET Microscopy

Using Microscopy for Deep In Vivo Brain Imaging

Microscopy’s Involvement in Brain Imaging

Differentiating Tumors using Microscopy

Expansion Microscopy in Neurology

Scanning Helium Microscopy: An Overview

X-ray Microscopy: An Overview

Diagnosing Alzheimer's Using Microscopy

Intravital Kidney Microscopy: An Overview

Investigating the Applications of Meoscopy

What is Expansion Microscopy?

Live-Cell Imaging with Super-Resolution Microscopy

Understanding the Brain Through Electron Microscopy

How Do Spectrometer Accessories Elevate Instrument Capabilities?

Microscopy in Oncology Research: Visualizing Tumor Microenvironments

Latest Microscopy News and Research

Bridge RNA: The Revolutionary Tool in Genetic Recombination

In a leap forward for genetic engineering, a team of researchers from the Arc Institute have discovered the bridge recombinase mechanism, a precise and powerful tool to recombine and rearrange DNA in a programmable way.

27 Jun 2024

Fruit Fly Motor Circuitry Revealed Through Advanced Mapping Techniques

Work is underway on a wiring diagram of the motor circuits in the central nervous system that control muscles in fruit flies.

27 Jun 2024

Breakthrough in Understanding Connexin-Drug Interactions

Researchers have gained new knowledge of how drugs bind to connexin molecules. These molecules form channels that allow neighboring cells to send direct messages to one another.

27 Jun 2024

New Insights into How Cells Fine-Tune Protein Assembly

Imagine the body as a bustling factory constantly assembling proteins, the building blocks that keep everything running smoothly.

26 Jun 2024

Leica Microsystems' Aivia 14 Enhances 3D Multiplexed Image Analysis

Leica Microsystems, a leading provider of microscopy and scientific instrumentation, has released version 14 of Aivia, its flagship image analysis solution.

22 Jun 2024

Specific Population of "Time Cells" Found to be Essential for Learning Complex Behaviors

A sense of time is fundamental to how we understand, recall, and interact with the world.

19 Jun 2024

Breakthrough Imaging Reveals the Dynamics of the Brain's Fast-Acting Kainate Receptor

New groundbreaking images of one of the brain's fastest-acting proteins are providing critical clues that may lead to the development of targeted therapies to treat epilepsy and other brain disorders.

18 Jun 2024

Stem cell-based kidney chip revolutionizes disease modeling and research

An organ-on-chip system containing a kidney glomerulus using human-induced pluripotent stem cells and an ultrathin membrane.

17 Jun 2024

Johns Hopkins Scientists Engineer Synthetic Cells to Mimic Symmetry Breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

14 Jun 2024

Super-Cooled Brain Cell Molecules Shed Light on Epilepsy Drug Action

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius -; nearly twice as cold as the coldest places in Antarctica -; scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

11 Jun 2024

Study Finds Essential Role of Orco Protein in Ant Olfactory Neuron Survival and Social Interaction

While smell plays a considerable role in the social interactions of humans-;for instance, signaling fear or generating closeness-;for ants, it is vitally important.

10 Jun 2024

Cellular Architecture Dictates T Cell Fate in Immune Response

From the outside, most T cells look the same: small and spherical. Now, a team of researchers led by Berend Snijder from the Institute of Molecular Systems Biology at ETH Zurich has taken a closer look inside these cells using advanced techniques.

7 Jun 2024

New mosTF Microscopy System Enhances Real-Time Brain Plasticity Research

The brain's ability to learn comes from "plasticity," in which neurons constantly edit and remodel the tiny connections called synapses that they make with other neurons to form circuits.

6 Jun 2024

New Microscopy Reveals Secrets of SARS-CoV-2 Replication

Recent research published in Nature Communications by a Stanford University team may provide more accuracy in drug development by examining at the nanoscale how the SARS-CoV-2 virus replicates in cells.

4 Jun 2024

Neurons in the Visual System of Flies Exhibit Surprisingly Heterogeneous Wiring

Analysis of the connectome of Drosophila melanogaster provides new insights into how its visual system is organized / Research contribution by the FlyWire Consortium

4 Jun 2024

Structural Insights into a Novel Gene-Editing Tool

Yutaro Shuto, Ryoya Nakagawa, and Osamu Nureki of the University of Tokyo conducted collaborative research to ascertain the spatial organization of different processes within a unique gene-editing instrument known as “prime editor.”

30 May 2024

Newly Discovered CD8-fit Cells Could Revolutionize Cancer Treatment

A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies.

30 May 2024

LoCoHD: A Novel Method for Comparative Protein Structure Analysis

In a paper recently published in Nature Communications, the HUN-REN-ELTE Protein Modeling Research Group (Institute of Chemistry) has laid the foundations for a mathematical method, allowing the computer-assisted comparison of the three-dimensional structures of proteins.

30 May 2024

Unmasking XPD’s Mechanism in DNA Damage Detection and Repair

The way the protein XPD recognizes severe DNA damage and regulates its repair was uncovered by researchers at the University of Würzburg, under the direction of Caroline Kisker and Claudia Höbartner.

29 May 2024