Overview
LAP is a photoinitiator that dissolves in water and is used to start the polymerization of hydrogels or bioinks. Due to its higher cytocompatibility, LAP—which is photo crosslinked with 405nm blue light—is frequently chosen over Irgacure 2959.
LAP is a cytocompatible, water-soluble photoinitiator used to create hydrogels or bioinks. Due to its higher water solubility, higher rates of polymerization with 365 nm light, and absorbance at 400 nm allowing for polymerization with visible light, this photoinitiator is preferred over Irgacure 2959 for biological applications.
It has been demonstrated that the enhanced polymerization kinetics allow for cell encapsulation at lower initiator concentrations and longer wavelength light, which increases cell viability and lowers initiator toxicity.
This LAP item is regarded as non-sterile. It is advised to sterile filter the system or add antibiotics to the cell culture setup. Resuspend the desired amount of LAP and filter through tiny 0.2-micron button filters to sterilize the process. Within two weeks, use the sterile photoinitiator.
There is 500 mg of dry powder in this product.
Storage/Stability
The product is delivered in gel packs. Keep the product between 2 and 8 °C. Measure out the necessary quantity of powder for solubilization. Utilize after solubilization within two weeks.
At 2–8 °C, non-solubilized dry powder is stable for more than a year.