Overview
This Type III Collagen product is obtained from the human placenta and refined utilizing a multi-step process. It contains around 85% Type III collagen and the rest is Type I collagen. The product comes in the form of a non-sterile powder weighing 10 mg.
Type III collagen product is offered in easy-to-use packaging for use and storage.
Type III Collagen offers structure and strength to connective tissue, and is found in several places in the body, particularly lungs, skin, intestinal walls, and the walls of blood vessels. Initially, Collagen III is produced as procollagen and is a protein comprising three pro-alpha1(III) chains that develop the triple-stranded, rope-like molecule.
Once the synthesis is done, the procollagen molecule is altered by the cell. Enzymes alter the amino acids proline and lysine present in the protein strands by the addition of chemical groups. They are essential for the strands to develop a stable molecule and then further crosslink to other molecules in the external part of the cell.
The Type III procollagen molecules are liberated from the cell and are being processed by enzymes that have the potential to clip small segments off to the end of the molecules to develop mature collagen. Then, the mature collagen molecules get arranged into fibrils. Cross-linking between molecules creates a highly stable fibril, which adds up to the collagen’s tissue-strengthening function.
Normally, Type III Collagen is utilized as a thin coating on tissue culture surfaces or as a control. This product is generally utilized in vitro as a substrate scaffold to improve cell adherence, attachment, and proliferation. Also, Type III collagen might be utilized to culture a range of cell types.
Source: Advanced BioMatrix
Parameter, Testing, and Method |
Type III Collagen Powder #5019 |
Form |
Powder |
Package Size |
10 mg |
Storage Temperature |
2-10 °C |
Shelf Life |
Minimum of 6 months from date of receipt |
Adventitious Agents - by RPR |
Human source has been tested and found negative for Hepatitis B, C, Syphilis and immunodeficiency virus-1. |
Electrophoretic Pattern - Coomassie Blue |
Characteristic |
Endotoxin (LAL) |
≤ 10.0 EU/mL |
Source |
Human Placenta |